MetabolicMarkers

Educational content only, not medical advice. We are not a medical provider; review your results with a licensed physician. Details

Current promotion

Comprehensive Cardiac Risk Blood Workup: Up to 94 Biomarkers

The two deepest Heart Health Risk tiers, 17 to 24 tests across blood and urine, for adults who want the fullest cardiovascular picture.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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High and High Plus tiers are $454.36 and $1,008 with the 20% promotion (list $567.95 and $1,260); lighter tiers start at $75.96, promotional pricing at time of writing.

At a glance

A comprehensive cardiac risk workup goes beyond a basic cholesterol check: the High and High Plus Heart Health Risk tiers measure 83 to 94 biomarkers across 17 to 24 tests, using blood, urine, and other specimen types. They are aimed at adults with a family history of heart disease, existing risk factors, or a preference for the most complete dataset to review with their doctor. Lighter 3-test and 11-test tiers are available on the same partner page for anyone starting smaller.

Best suited for

  • Adults with a family history of heart disease who want broad screening data to review with their doctor
  • People already monitoring blood pressure, blood sugar, or cholesterol who want one wide-net panel instead of many separate orders
  • Data-oriented testers who want the fullest available biomarker set, up to 24 tests and 94 biomarkers, as a personal baseline
  • Anyone whose doctor has suggested broader cardiovascular risk screening between visits

What's included

CVD - 3. High Heart Health Risk

17 tests, 83 biomarkers; blood, urine, and varied specimens

CVD - 4. High Heart Health Risk Plus

24 tests, 94 biomarkers; the most comprehensive tier

CVD - 2. Moderate Heart Health Risk

11 tests, 74 biomarkers; the partner's most popular tier

CVD - 1. Low Heart Health Risk

3 tests, 9 biomarkers; blood specimen, entry-level baseline tier

Deep-dive the key markers: LDL-C, HDL-C, Triglycerides, hs-CRP, ApoB, Lp(a)

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

LDL Cholesterol (mg/dL)

Commonly used reference ranges label LDL-C under 100 mg/dL optimal; ideal targets depend on your overall cardiovascular risk profile.

LDL Cholesterol reference ranges (mg/dL)
ZoneRange
Optimal0–100 mg/dL
Near optimal100–130 mg/dL
Borderline high130–160 mg/dL
High160–190 mg/dL
Very high190–220 mg/dL
HDL Cholesterol (mg/dL)

Commonly used cutoffs differ by sex: below 40 mg/dL is low for men, below 50 mg/dL for women; 60 mg/dL and above is generally considered protective-range.

HDL Cholesterol reference ranges (mg/dL)
ZoneRange
Low0–40 mg/dL
Acceptable40–60 mg/dL
Optimal60–100 mg/dL
Triglycerides (mg/dL)

Commonly used reference ranges place fasting triglycerides under 150 mg/dL; results are highly sensitive to recent meals, alcohol, and carbohydrate intake.

Triglycerides reference ranges (mg/dL)
ZoneRange
Optimal0–100 mg/dL
Normal100–150 mg/dL
Borderline high150–200 mg/dL
High200–400 mg/dL

The importance of testing

If cardiovascular risk runs in your family, or you are already tracking blood pressure or blood sugar concerns with a doctor, a wider biomarker net can be more informative than a minimal screen. The partner's overview emphasizes how interconnected these systems are, blood sugar, blood pressure, and hormone balance all influence how hard the heart works, so the deeper tiers sample across that whole metabolic picture rather than one corner of it.

The High tier runs 17 tests covering 83 biomarkers across blood, urine, and varied specimen types; High Plus expands to 24 tests and 94 biomarkers, the most comprehensive option in this promotion. If the top tiers are more than you need, the Moderate tier (11 tests, 74 biomarkers) remains the partner's most popular middle ground, and a 3-test Low tier covers the basics.

A comprehensive baseline is most useful as a reference point. Establish it once, then use follow-up testing to watch how specific markers associated with cardiovascular risk respond to lifestyle changes or to steps your doctor recommends. None of this testing confirms a condition, it gives you and your doctor better raw material for decisions.

Part of our complete guide to Heart Health Lab Tests — browse every panel and biomarker guide in this hub.

Promo code

CVD20OFF

Save 20% with code CVD20OFF, current promotion; confirm final pricing on the partner page.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

Order Now

Frequently asked questions

What does a comprehensive cardiac risk workup include?

In this promotion, the two deepest tiers include 17 tests covering 83 biomarkers and 24 tests covering 94 biomarkers, collected via blood, urine, and varied specimen types. The exact test list for each tier is itemized on the partner page before checkout.

Is the biggest panel always the right choice?

Not necessarily, the right tier depends on your goals, budget, and what your doctor wants to see. The Moderate tier (11 tests, 74 biomarkers) is the partner's most popular choice, while the High Plus tier suits people who want the most complete single snapshot.

Do I need a doctor's order to buy these panels?

No separate doctor's visit is required to order, each tier can be added to your cart and purchased directly through the partner's online checkout. Plan to share results with your own doctor, particularly any values flagged out of range.

Can these tests confirm heart disease?

No, they measure biomarkers associated with cardiovascular risk and are not intended to confirm any condition or substitute for medical care. Their job is to surface numbers and trends you can review with a clinician.

Can I order direct-to-consumer lab tests in every US state?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, and residents of those states may be blocked at the partner's checkout. Most other US states allow online ordering with a visit to a local draw site.

How much do the comprehensive tiers cost?

At the time of writing, the High tier is $454.36 and High Plus is $1,008 after the 20% promotion with code CVD20OFF (list $567.95 and $1,260). Confirm current pricing and the code on the partner page, since promotions change.

References

  1. [1] LDL: The 'Bad' Cholesterol — MedlinePlus (National Library of Medicine, NIH)
  2. [2] Low-density lipoproteins cause atherosclerotic cardiovascular disease: A consensus statement from the European Atherosclerosis Society Consensus Panel — European Heart Journal
  3. [3] Familial Hypercholesterolemia — GeneReviews, NCBI Bookshelf (NIH)
  4. [4] Hypercholesterolemia — StatPearls, NCBI Bookshelf (NIH)
  5. [5] Low HDL Cholesterol — StatPearls, NCBI Bookshelf (NIH)
  6. [6] HPS2-THRIVE, AIM-HIGH and dal-OUTCOMES: HDL-cholesterol under attack — Global Cardiology Science & Practice
  7. [7] Metabolic syndrome — MedlinePlus (National Library of Medicine, NIH)
  8. [8] Cholesterol Levels: What You Need to Know — MedlinePlus (National Library of Medicine, NIH)
  9. [9] Triglycerides — MedlinePlus (National Library of Medicine, NIH)
  10. [10] Hypertriglyceridemia — StatPearls, NCBI Bookshelf (NIH/NLM)
  11. [11] High Blood Triglycerides — National Heart, Lung, and Blood Institute (NIH)
  12. [12] C-Reactive Protein (CRP) Test — MedlinePlus (National Library of Medicine, NIH)
  13. [13] Assessing Cardiovascular Risk with C-Reactive Protein — Johns Hopkins Medicine
  14. [14] C-Reactive Protein: Clinical Relevance and Interpretation — StatPearls, NCBI Bookshelf (NIH/NLM)
  15. [15] Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease — F1000Research
  16. [16] Apolipoprotein B in the Risk Assessment, Diagnosis, and Treatment of Cardiometabolic Diseases — Cardiology and Cardiovascular Medicine
  17. [17] ACC/AHA Issue Updated Guideline for Managing Lipids, Cholesterol — American Heart Association
  18. [18] Discordantly normal ApoB relative to elevated LDL-C in persons with metabolic disorders: A marker of atherogenic heterogeneity — American Journal of Preventive Cardiology
  19. [19] Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases — Cardiovascular Drugs and Therapy
  20. [20] Lipoprotein(a) Testing Trends in the United States 2015-2024: An Analysis of 300 Million Individuals — JACC: Advances
  21. [21] About Lipoprotein (a) — Centers for Disease Control and Prevention (CDC)

Reviewed by

Jason August

Jason August

Founder & Editorial Lead

Jason August is the founder of Metabolic Markers and its parent company, Advancing Development. He has spent his career building and scaling real-world ventures, including as a founding team member at Build-A-Bear Workshop during its growth from startup to global public company, and since then across capital, real estate, adaptive reuse, and hospitality. He founded Metabolic Markers to make blood-biomarker testing easier to understand and access, and oversees the site’s content and editorial accuracy. Jason is not a medical professional; all content on this site is educational, reviewed for accuracy, and never a substitute for advice from a licensed physician.

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