MetabolicMarkers

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Current promotion

Comprehensive Wellness Blood Test Panel with Vitamin D

A full-body baseline in one blood draw: blood counts, metabolism, cholesterol, thyroid, iron, and vitamin D status.

Affiliate disclosure: we earn a commission when you purchase lab tests through links on this site, at no extra cost to you. Learn more

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Panels from $68; the featured CWP + Vitamin D option is $99 (regularly $125.95) and the advanced lipid option is $158 (regularly $220.95), promotional pricing at time of writing.

At a glance

The Comprehensive Wellness Profile + Vitamin D is a broad blood test panel that measures 66 biomarkers across six lab tests: a complete blood count with differential and platelets, a comprehensive metabolic panel, a lipid panel with ratios, total iron, thyroid-stimulating hormone (TSH), and 25-hydroxyvitamin D with D2 and D3 fractions. It is built for adults who want a wide-angle baseline of blood cell health, metabolism, kidney and liver markers, cholesterol, thyroid function, and vitamin D status from a single visit. Two sibling options on the same offer let you skip vitamin D for a lower price or step up to a Cardio IQ advanced lipid panel with ApoB and Lp(a).

Best suited for

  • Adults who want a broad annual baseline of core blood markers without ordering tests one by one
  • Anyone tracking metabolic markers, glucose, cholesterol, liver and kidney values, over time
  • People with limited sun exposure or other reasons to check their vitamin D status
  • Those preparing for a physical who want organized results to review with their doctor
  • Budget-conscious testers comparing tiered options: base profile, + vitamin D, or + advanced lipids

What's included

Comprehensive Wellness Profile (CWP) + Vitamin D

6 tests, 66 biomarkers: CBC with differential and platelets, comprehensive metabolic panel, total iron, lipid panel with ratios, TSH, and QuestAssureD 25-hydroxyvitamin D total with D2 and D3.

Comprehensive Wellness Profile (CWP) + Cardio IQ Advanced Lipid Panel

8 tests, 70 biomarkers: the core wellness profile plus Cardio IQ Apolipoprotein B, Cardio IQ Lipid Panel, Cardio IQ Lipoprotein (a), and Cardio IQ Lipoprotein Fractionation by Ion Mobility.

Comprehensive Wellness Profile (CWP)

5 tests, 63 biomarkers: CBC with differential and platelets, comprehensive metabolic panel, total iron, lipid panel with ratios, and TSH.

Deep-dive the key markers: Fasting Glucose, ApoB, LDL-C, HDL-C, Triglycerides, Lp(a), TSH, Vitamin D, eGFR, ALT

Key biomarker ranges

Commonly used adult reference ranges for markers this panel measures, labs vary, so always interpret results against your lab's stated ranges and with your doctor.

Fasting Glucose (mg/dL)

Commonly used reference ranges place fasting glucose at 70–99 mg/dL; results vary with sleep, stress, and recent illness, and labs differ slightly.

Fasting Glucose reference ranges (mg/dL)
ZoneRange
Low50–70 mg/dL
Optimal70–100 mg/dL
Prediabetic range100–126 mg/dL
Diabetic range126–160 mg/dL
Apolipoprotein B (mg/dL)

Commonly used reference ranges favor ApoB below ~90 mg/dL; people with higher baseline cardiovascular risk are often advised toward lower targets.

Apolipoprotein B reference ranges (mg/dL)
ZoneRange
Optimal0–90 mg/dL
Borderline high90–110 mg/dL
High110–160 mg/dL
LDL Cholesterol (mg/dL)

Commonly used reference ranges label LDL-C under 100 mg/dL optimal; ideal targets depend on your overall cardiovascular risk profile.

LDL Cholesterol reference ranges (mg/dL)
ZoneRange
Optimal0–100 mg/dL
Near optimal100–130 mg/dL
Borderline high130–160 mg/dL
High160–190 mg/dL
Very high190–220 mg/dL

The importance of testing

A broad wellness panel condenses the tests most commonly reviewed at an annual physical into a single blood draw. The complete blood count with differential and platelets looks at red cells, white cells, and platelets, markers associated with anemia, immune activity, and clotting. The comprehensive metabolic panel adds glucose, electrolytes, and kidney and liver markers such as eGFR, creatinine, and ALT, giving a wide view of how core organ systems are working.

The lipid panel with ratios reports total, LDL, and HDL cholesterol plus triglycerides, the standard markers used to gauge cardiovascular risk, while TSH screens thyroid function and total iron reflects iron status. The added 25-hydroxyvitamin D test, with separate D2 and D3 fractions, measures a nutrient involved in bone health and immune function that adults with limited sun exposure often want to keep an eye on.

Numbers like these are most useful as a trend. A baseline today gives you something to compare against after a diet change, a new training block, or a new prescription, and repeat testing shows whether values are drifting toward or away from their reference ranges. Bring any flagged results to your doctor, out-of-range values are conversation starters to review with a clinician, not conclusions.

If heart health is your main focus, the same offer includes an upgraded version that swaps the standard lipid panel for a Cardio IQ advanced lipid panel, adding apolipoprotein B, lipoprotein (a), and lipoprotein fractionation by ion mobility, markers associated with cardiovascular risk that standard cholesterol tests do not capture.

Part of our complete guide to Metabolic Health Lab Tests — browse every panel and biomarker guide in this hub.

Promo code

ULTA4E20

Save with code ULTA4E20, current promotion shown on the partner page; confirm the final price and code at checkout.

Ready to get your numbers? Order online, visit a nearby draw site, and receive private results to review with your doctor.

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Frequently asked questions

What does the Comprehensive Wellness Profile + Vitamin D measure?

It measures 66 biomarkers across six tests: a complete blood count with differential and platelets, a comprehensive metabolic panel covering glucose, electrolytes, and kidney and liver markers, a lipid panel with ratios, total iron, thyroid-stimulating hormone (TSH), and 25-hydroxyvitamin D with D2 and D3 fractions. Together they provide a broad snapshot of blood health, metabolic function, cardiovascular risk markers, thyroid activity, iron levels, and vitamin D status.

Can I order this panel without a doctor's visit?

Yes, the partner sells these panels direct-to-consumer online, so you can select an option, order it, and have blood drawn at a local lab location without booking a doctor's appointment first. Your results are still best reviewed with your own clinician, especially if anything comes back flagged.

What is the difference between the three panel options?

The base Comprehensive Wellness Profile covers the CBC, metabolic panel, total iron, lipid panel with ratios, and TSH; the + Vitamin D version adds a 25-hydroxyvitamin D test with D2 and D3 fractions; and the + Cardio IQ Advanced Lipid Panel version upgrades the cholesterol testing with apolipoprotein B, lipoprotein (a), and lipoprotein fractionation by ion mobility. Choose based on whether vitamin D status or deeper cardiovascular risk markers matter more to you.

Do I need to fast before this blood draw?

Fasting requirements depend on the specific tests, and panels that include glucose and a lipid panel are often drawn after an overnight fast for the most consistent results. Follow the preparation instructions the lab provides with your order, and keep conditions similar between draws if you plan to compare results over time.

Is this panel available in every US state?

No, direct-to-consumer lab testing is restricted or prohibited in New York, New Jersey, and Rhode Island, so residents of those states may be blocked at the partner's checkout. Elsewhere, availability depends on having a participating draw location nearby.

How often should I repeat a wellness panel like this?

Many people retest a broad panel like this once a year to build a trend line, or sooner after a meaningful change in diet, training, or medication. The right cadence is individual, so discuss retesting frequency with your doctor, particularly if any earlier results were out of range.

References

  1. [1] Hidden Risks behind Normal Fasting Glucose: Is It Significant? — Diabetes & Metabolism Journal (Korean Diabetes Association, via PMC)
  2. [2] Good to Know: Factors Affecting Blood Glucose — Clinical Diabetes, American Diabetes Association (via PMC)
  3. [3] Insulin Resistance & Prediabetes — National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  4. [4] Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease — F1000Research
  5. [5] Apolipoprotein B in the Risk Assessment, Diagnosis, and Treatment of Cardiometabolic Diseases — Cardiology and Cardiovascular Medicine
  6. [6] ACC/AHA Issue Updated Guideline for Managing Lipids, Cholesterol — American Heart Association
  7. [7] Discordantly normal ApoB relative to elevated LDL-C in persons with metabolic disorders: A marker of atherogenic heterogeneity — American Journal of Preventive Cardiology
  8. [8] LDL: The 'Bad' Cholesterol — MedlinePlus (National Library of Medicine, NIH)
  9. [9] Low-density lipoproteins cause atherosclerotic cardiovascular disease: A consensus statement from the European Atherosclerosis Society Consensus Panel — European Heart Journal
  10. [10] Familial Hypercholesterolemia — GeneReviews, NCBI Bookshelf (NIH)
  11. [11] Hypercholesterolemia — StatPearls, NCBI Bookshelf (NIH)
  12. [12] Low HDL Cholesterol — StatPearls, NCBI Bookshelf (NIH)
  13. [13] HPS2-THRIVE, AIM-HIGH and dal-OUTCOMES: HDL-cholesterol under attack — Global Cardiology Science & Practice
  14. [14] Metabolic syndrome — MedlinePlus (National Library of Medicine, NIH)
  15. [15] Cholesterol Levels: What You Need to Know — MedlinePlus (National Library of Medicine, NIH)
  16. [16] Triglycerides — MedlinePlus (National Library of Medicine, NIH)
  17. [17] Hypertriglyceridemia — StatPearls, NCBI Bookshelf (NIH/NLM)
  18. [18] High Blood Triglycerides — National Heart, Lung, and Blood Institute (NIH)
  19. [19] Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases — Cardiovascular Drugs and Therapy
  20. [20] Lipoprotein(a) Testing Trends in the United States 2015-2024: An Analysis of 300 Million Individuals — JACC: Advances
  21. [21] About Lipoprotein (a) — Centers for Disease Control and Prevention (CDC)
  22. [22] TSH (Thyroid-stimulating hormone) Test — MedlinePlus (National Library of Medicine, NIH)
  23. [23] Thyroid Function Tests — American Thyroid Association
  24. [24] Subclinical Hypothyroidism — StatPearls, NCBI Bookshelf (NIH/NLM)
  25. [25] Vitamin D - Health Professional Fact Sheet — NIH Office of Dietary Supplements
  26. [26] Evaluation, Treatment, and Prevention of Vitamin D Deficiency: An Endocrine Society Clinical Practice Guideline — Endocrine Society (Journal of Clinical Endocrinology & Metabolism)
  27. [27] Vitamin D - Health Professional Fact Sheet — NIH Office of Dietary Supplements
  28. [28] Physiology, Glomerular Filtration Rate — StatPearls, NCBI Bookshelf (NIH)
  29. [29] Stages of Chronic Kidney Disease (CKD) — National Kidney Foundation
  30. [30] What Is Chronic Kidney Disease in Adults? — NIDDK (NIH)
  31. [31] Is It Time for a Requiem for Creatine Supplementation-Induced Kidney Failure? A Narrative Review — Nutrients
  32. [32] Estimated GFR (eGFR) Test: Kidney Function Levels, Stages, and What to Do Next — National Kidney Foundation
  33. [33] Alanine Aminotransferase (ALT) Test — StatPearls, NCBI Bookshelf (NIH)
  34. [34] Definition & Facts of NAFLD & NASH — NIDDK (NIH)
  35. [36] Liver Function Tests — StatPearls, NCBI Bookshelf (NIH)

Reviewed by

Jason August

Jason August

Founder & Editorial Lead

Jason August is the founder of Metabolic Markers and its parent company, Advancing Development. He has spent his career building and scaling real-world ventures, including as a founding team member at Build-A-Bear Workshop during its growth from startup to global public company, and since then across capital, real estate, adaptive reuse, and hospitality. He founded Metabolic Markers to make blood-biomarker testing easier to understand and access, and oversees the site’s content and editorial accuracy. Jason is not a medical professional; all content on this site is educational, reviewed for accuracy, and never a substitute for advice from a licensed physician.

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